Grade

Histological Grading Scheme for Endometrial Carcinoma

I

Well-differentiated with < 5% solid area, prominent / easily recognizable glandular pattern.

II

Moderately differentiated with 6-50% solid areas, mixed solid and glandular pattern.

III

>50% solid or entirely undifferentiated, minimal or no gland formation.

Note

Significant nuclear atypia or nuclear atypia inappropriate for  architectural grade raises Grade I and Grade II tumors by one grade.  Do not include metaplastic squamous areas in FIGO grade

Category

Histologic Features

I

(Mild)

Mild interstitial fibrosis and tubular atrophy without (a) or with (b) specific vascular changes suggesting chronic rejection

II

(Moderate)

Moderate interstitial fibrosis and tubular atrophy without (a) or with (b) specific vascular changes suggesting chronic rejection

III

(Severe)

Severe interstitial fibrosis and tubular atrophy without (a) or with (b) specific vascular changes suggesting chronic rejection