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Response Options to Tumor Site (select all that apply)


___ Cardia

___ Fundus

       + ___ Anterior wall

       + ___ Posterior wall

___ Body

       + ___ Anterior wall

       + ___ Posterior wall

       + ___ Lesser curvature

       + ___ Greater curvature

___ Antrum

       + ___ Anterior wall

       + ___ Posterior wall

       + ___ Lesser curvature

       + ___ Greater curvature

___ Pylorus

___ Other (specify): ____________________________

___ Not specified


Response Options to Histologic Type

___ Adenocarcinoma

       Lauren classification of adenocarcinoma:

               ___ Intestinal type

               ___ Diffuse type (includes signet-ring carcinoma, classified as >50% signet-ring cells)

               ___ Mixed (approximately equal amounts of intestinal and diffuse)

       + Alternative optional classification (based on WHO classification):

               + ___ Tubular (intestinal) adenocarcinoma

       + ___ Poorly cohesive carcinoma (including signet-ring cell carcinoma and other variants)

               + ___ Mucinous adenocarcinoma (>50% mucinous)

               + ___ Papillary adenocarcinoma

+ ___Mixed carcinoma (mixture of discrete glandular (tubular/papillary) and signet-ring/poorly cohesive cellular histological components)

___ Hepatoid adenocarcinoma

___ Carcinoma with lymphoid stroma (medullary carcinoma)

___ Large cell neuroendocrine carcinoma

___ Small cell neuroendocrine carcinoma

___ Neuroendocrine carcinoma (poorly differentiated)#

___ Mixed adenoneuroendocrine carcinoma

___ Squamous cell carcinoma

___ Adenosquamous carcinoma

___ Undifferentiated carcinoma

___ Other histologic type not listed (specify): _________________________________

# Note: Select this option only if large cell or small cell cannot be determined.



Response Options to "tumor extension"

___ Cannot be assessed

___ No evidence of primary tumor

___ High-grade dysplasia/carcinoma in situ

___ Tumor invades lamina propria and/or muscularis mucosae

___ Tumor invades submucosa

___ Tumor invades muscularis propria

___ Tumor invades subserosal connective tissue, without involvement of visceral peritoneum or adjacent structures

___ Tumor invades serosa (visceral peritoneum)

___ Tumor invades adjacent structures (specify): ______________________

Response Options to “Treatment effect”

Description

Tumor Regression Score

No viable cancer cells (complete response)

0

Single cells or rare small groups of cancer cells (near complete response)

1

Residual cancer with evident tumor regression, but more than single cells or rare small groups of cancer cells (partial response)

2

Extensive residual cancer with no evident tumor regression (poor or no response)

3


Gastrointestinal


Staging


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