Response Options to Tumor Site (select all that apply)
___ Cardia
___ Fundus
+ ___ Anterior wall
+ ___ Posterior wall
___ Body
+ ___ Anterior wall
+ ___ Posterior wall
+ ___ Lesser curvature
+ ___ Greater curvature
___ Antrum
+ ___ Anterior wall
+ ___ Posterior wall
+ ___ Lesser curvature
+ ___ Greater curvature
___ Pylorus
___ Other (specify): ____________________________
___ Not specified
Response Options to Histologic Type
___ Adenocarcinoma
Lauren classification of adenocarcinoma:
___ Intestinal type
___ Diffuse type (includes signet-ring carcinoma, classified as >50% signet-ring cells)
___ Mixed (approximately equal amounts of intestinal and diffuse)
+ Alternative optional classification (based on WHO classification):
+ ___ Tubular (intestinal) adenocarcinoma
+ ___ Poorly cohesive carcinoma (including signet-ring cell carcinoma and other variants)
+ ___ Mucinous adenocarcinoma (>50% mucinous)
+ ___ Papillary adenocarcinoma
+ ___Mixed carcinoma (mixture of discrete glandular (tubular/papillary) and signet-ring/poorly cohesive cellular histological components)
___ Hepatoid adenocarcinoma
___ Carcinoma with lymphoid stroma (medullary carcinoma)
___ Large cell neuroendocrine carcinoma
___ Small cell neuroendocrine carcinoma
___ Neuroendocrine carcinoma (poorly differentiated)#
___ Mixed adenoneuroendocrine carcinoma
___ Squamous cell carcinoma
___ Adenosquamous carcinoma
___ Undifferentiated carcinoma
___ Other histologic type not listed (specify): _________________________________
# Note: Select this option only if large cell or small cell cannot be determined.
Response Options to "tumor extension"
___ Cannot be assessed
___ No evidence of primary tumor
___ High-grade dysplasia/carcinoma in situ
___ Tumor invades lamina propria and/or muscularis mucosae
___ Tumor invades submucosa
___ Tumor invades muscularis propria
___ Tumor invades subserosal connective tissue, without involvement of visceral peritoneum or adjacent structures
___ Tumor invades serosa (visceral peritoneum)
___ Tumor invades adjacent structures (specify): ______________________
Response Options to “Treatment effect”
Description |
Tumor Regression Score |
No viable cancer cells (complete response) |
0 |
Single cells or rare small groups of cancer cells (near complete response) |
1 |
Residual cancer with evident tumor regression, but more than single cells or rare small groups of cancer cells (partial response) |
2 |
Extensive residual cancer with no evident tumor regression (poor or no response) |
3 |