* Response Options to "Microscopic tumor extension"

___ Cannot be assessed (TX)

___ No evidence of primary tumor (T0)

___ Carcinoma in situ (Tis)

___ Tumor invades lamina propria

___ Tumor invades muscularis mucosae

___ Tumor invades submucosa

___ Tumor invades into but not through the sphincter muscle

___ Tumor invades into but not through the muscularis propria of rectum

___ Tumor invades through sphincter muscle into perianal or perirectal soft tissue

without involvement of adjacent structures

___ Tumor directly invades adjacent structures (T4) (specify): ______

___ Tumor invades perianal skin

Tumor Regression Grading System

__ No prior treatment

__ No viable cancer cells                                         0 (Complete response)

__ Single cells or small groups of cancer cells                1 (Moderate response)

__ Residual cancer outgrown by fibrosis                        2 (Minimal response)

__ Minimal or no tumor kill; extensive residual cancer         3 (Poor response)

Gastrointestinal

Staging

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