Response Options to “Histologic Type”

___ Squamous cell carcinoma, NOS

___ Squamous cell carcinoma, keratinizing

___ Squamous cell carcinoma, nonkeratinizing

___ Squamous cell carcinoma, basaloid

___ Squamous cell carcinoma, verrucous

___ Squamous cell carcinoma, warty

___ Squamous cell carcinoma, papillary

___ Squamous cell carcinoma, lymphoepithelioma-like

___ Squamous cell carcinoma, squamotransitional

___ Endocervical adenocarcionoma, usual type

___ Mucinous carcinoma, NOS

___ Mucinous carcinoma, intestinal type

___ Mucinous carcinoma, signet-ring cell type

___ Mucinous carcinoma, gastric type

___ Villoglandular carcinoma

___ Endometrioid carcinoma

___ Clear cell carcinoma

___ Serous carcinoma

___ Mesonephric carcinoma

___ Adenocarcinoma admixed with neuroendocrine carcinoma

___ Adenosquamous carcinoma

___ Adenosquamous carcinoma, glassy cell variant

___ Adenoid cystic carcinoma

___ Adenoid basal carcinoma

___ Small cell neuroendocrine carcinoma

___ Large cell neuroendocrine carcinoma

___ Undifferentiated carcinoma

___ Carcinosarcoma

___ Other histologic type not listed (specify): _________________________

___ Carcinoma, type cannot be determined

*Note: The depth of invasion is measured from its HSIL origin, that is, from the base of the epithelium either surface or glandular that is involved by HSIL to the deepest point of invasion. If the invasive focus or foci are not in continuity with the dysplastic epithelium, the depth of invasion should be measured from the deepest focus of tumor invasion to the base of the nearest dysplastic crypt or surface epithelium. If there is no obvious epithelial origin, the depth is measured from the deepest focus of tumor invasion to the base of the nearest surface epithelium, regardless of whether it is dysplastic or not. In situations where carcinomas are exclusively or predominantly exophytic, there may be little or no invasion of the underlying stroma. These should not be regarded as in situ lesions and the tumor thickness (from the surface of the tumor to the deepest point of invasion) should be measured in such cases. The depth of invasion below the level of the epithelial origin should not be provided in these cases as this may not truly reflect the biological potential of such tumors. If it is impossible to measure the depth of invasion, eg, in ulcerated tumors or in some adenocarcinomas, the tumor thickness may be measured instead, and this should be clearly stated on the pathology report along with an explanation for providing the thickness rather than the depth of invasion.

Horizontal extent: The longitudinal extent (length) of horizontal extent is measured in the superior-infer ior plane (ie, from the endocervical to ectocervical aspects of the section), whereas the circumferential extent (width) is measured or calculated perpendicular to the longitudinal axis of the cervix. If the tumor involves only 1 block, the circumferential extent (width) will be 2.5 mm to 3 mm (thickness of 1 block). When more than 1 block is involved, it is the product of the number of consecutive blocks with tumor and thickness of a block.

Response Options to “Other Tissue/ Organ Involvement” (select all that apply)

Note: Any organ not selected is either not involved or was not submitted.

___ Not applicable

___ Not identified

___ Right parametrium

___ Left parametrium

___ Parametrium (side not specified)

___ Vagina, upper two-thirds

___ Vagina, lower one-third

___ Vagina (location not specified)

___ Right ovary

___ Left ovary

___ Ovary (side not specified)

___ Right fallopian tube

___ Left fallopian tube

___ Fallopian tube (side not specified)

___ Pelvic wall

___ Bladder wall

___ Bladder mucosa

___ Rectal wall

___ Bowel mucosa

___ Omentum

___ Other organs/tissue (specify): ________________

___ Cannot be determined (explain):_________________________

**Note: Lymph nodes designated as pelvic, parametrial, obturator, internal iliac (hypogastric), external iliac, common iliac, sacral, presacral and para-aortic are considered regional lymph nodes. Any other involved nodes should be categorized as metastases (pM1) and commented on in the distant metastasis section. Presence of isolated tumor cells no greater than 0.2 mm in regional lymph node(s) is considered N0(i+). Reporting the number of lymph nodes with isolated tumor cells is required only in the absence of metastasis greater than 0.2 mm in other lymph nodes.

Gynecologic

Staging

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