Staging (Small Intestine)                                                
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Pathologic Staging (pTNM) AJCC 8th Edition

CAP Approved Gastrointestinal • Small Intestine 4.0.0.0


TNM Descriptors (required only if applicable) (select all that apply)

___ m (multiple primary tumors)

___ r (recurrent)

___ y (posttreatment)


Primary Tumor (pT)

___ pTX:        Primary tumor cannot be assessed

___ pT0:        No evidence of primary tumor

___ pTis:        High-grade dysplasia/carcinoma in situ

___ pT1        Tumor invades the lamina propria or submucosa

___ pT1a:        Tumor invades the lamina propria

___ pT1b:        Tumor invades the submucosa

___ pT2:        Tumor invades the muscularis propria

___ pT3:        Tumor invades through the muscularis propria into the subserosa or extends into the nonperitonealized perimuscular tissue (mesentery or retroperitoneum) without serosal penetration#

___ pT4:        Tumor perforates the visceral peritoneum or directly invades other organs or structures (e.g., other loops of small i ntestine, mesentery of adjacent loops of bowel, and abdominal wall by way of serosa; for duodenum only, invasion of pancreas or bile duct)

# Note: For T3 tumors, the nonperitonealized perimuscular tissue is, for the jejunum and ileum, part of the mesentery and, for the duodenum in areas where serosa is lacking, part of the interface with the pancreas.


Regional Lymph Nodes (pN)

___ pNX:        Regional lymph nodes cannot be assessed

___ pN0:        No regional lymph node metastasis

___ pN1:        Metastasis in one or two regional lymph nodes

___ pN2:        Metastasis in three or more regional lymph nodes


Distant Metastasis (pM) (required only if confirmed pathologically in this case)

___ pM1:        Distant metastasis

       Specify site(s), if known: ______________________


Summary of changes AJCC 7th to 8th ed.


Gastrointestinal


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