Pathologic Staging (pTNM)
CAP Approved Genitourinary • Urinary Bladder 4.0.0.0 (AJCC 8th ed.)
TNM Descriptors (required only if applicable) (select all that apply)
___ m (multiple primary tumors)
___ r (recurrent)
___ y (posttreatment)
Primary Tumor (pT)
___ pTX: |
Cannot be assessed |
___ pT0: |
No evidence of primary tumor |
___ pTa: |
Noninvasive papillary carcinoma |
___ pTis: |
Urothelial carcinoma in situ: “flat tumor” |
___ pT1: |
Tumor invades lamina propria (subepithelial connective tissue) |
pT2: Tumor invades muscularis propria (detrusor muscle)
___ pT2a: Tumor invades superficial muscularis propria (inner half) ___ pT2b: Tumor invades deep muscularis propria (outer half) pT3: Tumor invades perivesical tissue
___ pT3a: Microscopically
___ pT3b: Macroscopically (extravesicular mass)
pT4: Tumor invades any of the following: prostatic stroma, seminal vesicles, uterus, vagina, pelvic wall, abdominal wall
___ pT4a: Extravesical tumor invades directly into prostatic stroma, seminal vesicles, uterus or vagina
___ pT4b: Extravesical tumor invades pelvic wall, or abdominal wall
Regional Lymph Nodes (pN)
___ pNX: Lymph nodes cannot be assessed
___ pN0: No lymph node metastasis
___ pN1: Single regional lymph node metastasis in the true pelvis (perivesical, obturator, internal and external iliac or sacral lymph node)
___ pN2: Multiple regional lymph node metastasis in the true pelvis (perivesical, obturator, internal and external iliac or sacral lymph node metastasis)
___ pN3: Lymph node metastasis to the common iliac lymph nodes
Distant Metastasis (pM)
___ Not applicable
___ pM1: Distant metastasis (specify site(s) if known)
___ pM1a: Distant metastasis limited to lymph nodes beyond the common iliacs
___ pM1b: Non-lymph node distant metastases
Urinary Bladder CAP 4.0.0.0 summary of pTNM changes AJCC 7th to 8th edition
M1 now divided into M1a and M1b (“Distant metastasis limited to lymph nodes beyond the common iliacs” and “Non-lymph node distant metastases” respectively