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Staging (Colon NET)
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Staging (Colon NET)
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Pathologic Staging (pTNM) AJCC 8th ed. CAP Approved Endocrine • Neuroendocrine Tumors of the Colon and Rectum 4.0.0.0
TNM Descriptors (required only if applicable) (select all that apply)
___ m (multiple primary tumors)
___ r (recurrent)
___ y (posttreatment)
Primary Tumor (pT)#
___ pTX: Primary tumor cannot be assessed
___ pT0: No evidence of primary tumor
___ pT1: Tumor invades lamina propria or submucosa and is =2 cm
___ pT1a: Tumor ‹1 cm in greatest dimension ___ pT1b: Tumor 1 to 2 cm in greatest dimension
___ pT2: Tumor invades muscularis propria or is › 2 cm with invasion of lamina propria or submucosa
___ pT3: Tumor invades through the muscularis propria into the subserosa without penetration of overlying serosa
___ pT4: Tumor invades visceral peritoneum (serosa) or other organs or adjacent structures
# Note: For any T, add “(m)” for multiple tumors [TX(#) or TX(m), where X = 1–4 and # = number of primary tumors identified##]; for multiple tumors with different T, use the highest. ##Example: If there are two primary tumors, only one of which invades through the muscularis propria into the subserosal tissue without penetration of the overlying serosa, we define the primary tumor as either T3(2) or T3(m).
Regional Lymph Nodes (pN)
___ Cannot be assessed
___ pN0: No regional lymph node metastasis
___ pN1: Metastasis in regional lymph nodes
Distant Metastasis (pM)
___ Not applicable
___ pM1: Distant metastasis
___ pM1a: Metastasis confined to liver
___ pM1b: Metastasis in at least one extrahepatic site (eg, lung, ovary, nonregional lymph node, peritoneum, bone)
___ pM1c: Both hepatic and extrahepatic metastases (Specify site(s), if known)
Colon NET – BH- CAP 4.0.0.0 summary of pTNM changes AJCC 7th to 8th edition
- M1 is subcategorized into 3 categories (M1a is metastasis confined to the liver, M1b is metastasis in at least one extrahepatic site and M1c is defined as both hepatic and extrahepatic metastasis)