Pathologic Staging (pTNM)
CAP Approved Skin • Squamous Cell Carcinoma of the Skin 3.1.0.2
TNM Descriptors (required only if applicable) (select all that apply)
___ m (multiple primary tumors)
___ r (recurrent)
___ y (posttreatment)
Primary Tumor (pT)
___ pTX: Primary tumor cannot be assessed
___ pT0: No evidence of primary tumor
___ pTis: Carcinoma in situ
___ pT1: Tumor 2 cm or less in greatest dimension with fewer than two high-
risk features*
___ pT2: Tumor greater than 2 cm in greatest dimension with or without one
additional high-risk feature, or any size with two or more high-risk
features
___ pT3: Tumor with invasion of maxilla, mandible, orbit, or temporal bone
___ pT4: Tumor with invasion of skeleton (axial or appendicular) or perineural invasion
of skull base
* From the 7th edition AJCC Staging Manual: High risk features include poorly differentiated histologic grade, >2 mm Breslow depth, Clark anatomic level ≥ IV, perineural invasion and ear or hair-bearing lip tumor site.
Regional Lymph Nodes (pN)
___ pNX: Regional lymph nodes cannot be assessed
___ pN0: No regional lymph node metastasis
___ pN1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest
dimension
___ pN2: Metastasis in a single ipsilateral lymph node, more than 3 cm but not
more than 6 cm in greatest dimension; or in multiple ipsilateral lymph
nodes, none more than 6 cm in greatest dimension; or in bilateral or
contralateral lymph nodes, none more than 6 cm in greatest dimension
___ pN2a: Metastasis in a single ipsilateral lymph node, more than 3 cm but not
more than 6 cm in greatest dimension
___ pN2b: Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in
greatest dimension
___ pN2c: Metastasis in bilateral or contralateral lymph nodes, none more than 6
cm in greatest dimension.
___ pN3: Metastasis in a lymph node, more than 6 cm in greatest dimension
Distant Metastasis (pM)
___ Not applicable
___ pM1: Distant metastasis (documented in this specimen)