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e-Manual for Specimen Gross Examination in Surgical Pathology (4th Ed)
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Introduction |
Surgical Specimen Triage |
Conditions for Pathology Specimen Submission
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Purpose |
Parts |
Size/Quant |
Fixative |
Sterile |
Storage |
Transport |
Laboratory |
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Routine Histopathology |
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> 1 x 1 mm |
Yes (formalin) |
NR |
RT |
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Surgical Pathology Lab |
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Mircoorganism Culture |
1 |
|
No |
Yes |
RT |
ASAP |
Microbiology Lab |
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2 |
|
Yes |
NR |
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Surgical Pathology Lab |
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Immuno- flurescence |
1 |
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Yes |
NR |
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2 |
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No |
NR |
Freeze |
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Electron Microscopy |
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2 x < 0.5 mm |
Yes Glutaldehyde |
NR |
4 C |
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EM Lab |
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Cytogenetics (solid tumor) |
1 |
> 5 x 5 mm |
Yes |
NR |
RT |
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2 |
5 x 5 mm |
No |
Yes |
RT |
ASAP |
Cytogenetics Lab |
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Flow Cytometry |
1 |
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Yes |
NR |
RT |
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1 |
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No |
Yes |
4 C |
ASAP |
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Abbrev: ASAP = as soon as possible; EM = Electron Microscopy; NR = not required; RT = room temperature;
Specimen Triage for Special Diagnostic Studies in Pathology
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Diagnosis / Studies |
Routine Histology |
Tissue Culture |
Flow Cytometry |
Immuno- fluorescence |
Electron Microscopy |
Cyto- genetics |
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Comment |
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Lymphoma |
++ |
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++ |
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+ |
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All except Hodgkin’s lymphoma |
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Leukemia |
++ |
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++ |
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+ |
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Infectious disease |
++ |
++ |
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+/- |
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Mycobacteria |
++ |
++ |
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Whipple’s disease |
++ |
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++ |
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Cytomegalovirus |
++ |
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Herpes |
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Cervical HPV |
++ |
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PCR |
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C. diff colitis |
++ |
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Serology |
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Skin bullous disease |
+ |
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++ |
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Mesothelioma |
++ |
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++ |
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PD carcinoma |
++ |
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+ |
++ |
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Soft tissue sarcomas |
++ |
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+ |
++ |
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Abbrev: PCR = polymerase chain reaction; PD = poor differentiated (carcinomas); HPV = human papilloma virus.
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